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Genome Editing Core

Overview of Services

The Genome Editing Core (GEC) provides Joslin Diabetes Research Center (DCR) investigators with resources to manipulate the genome of laboratory mice with the aim of studying the genetics underlying diabetes and its complications.

The GEC maintains a facility for the generation of transgenic mouse models to aid in studying the genetic mechanisms underlying diabetes in vivo. The mouse modeling facility uses CRISPR/Cas9 or lentiviral RNAi constructs to introduce genome modifications to a variety of mouse lines in order to establish new models of the disease within a living mammalian system.

 

For CRISPR Screening services please click here

 *Please note, external pricing for this core is currenltly in the process of being worked on.

 

Publication Disclaimer

If any of your research has been supported in full or in part by a Joslin Diabetes Center DRC Core, please acknowledge the NIH/NIDDK grant as follows: "Supported by DRC, Grant No. P30 DK036836."

Leadership

Stephan Kissler, PhD Core Director   Stephan.Kissler@joslin.harvard.edu
Taylor Roberts Sr. Research Assistant   Taylor.Roberts@joslin.harvard.edu

Location and hours of operation

Hours Location

7:00 AM - 3:00 PM M-F 

 One Joslin Pl Rm 476
 Boston, MA 02215

Links and Resources

  1. Genome Editing Core
  2. https://www.ncbi.nlm.nih.gov/pubmed/29266098
  3. CRISPR Guide

Contacts

Name Role Phone Email Location
Stephan Kissler, PhD
Core Director
 
617-309-4071
 
Stephan.Kissler@joslin.harvard.edu
 

 
Taylor Roberts
Sr. Research Assistant
 
617-309-4072
 
Taylor.Roberts@joslin.harvard.edu
 
Lab 476