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Islet Isolation Core

Overview of Services

The main objective of the Islet Isolation Core is to provide Islets of Langerhans to investigators in the Boston area and beyond. By receiving islets from the Core one is assured of consistent high quality and purity of islets for experiments. The Core can isolate islets from rats and mice.This leaves the investigator to concentrate on experiments rather than the complexity of islet isolation.

The Core can buy the animals or the investigator can provide their own, such as special transgenic mice. Over the last 10 years the Core has isolated more than 10 million islets. We also provide training and advice. The Core can provide training not only for the isolation procedure but islet viability, islet size measurement, GSIS (Glucose Stimulated Insulin Secretion), STZ-induced diabetes, transplantation under the kidney capsule, and islet graft retrieval.


Susan Bonner-weir Director
Jennifer Hollister-Lock Manager 617 309 4391

Location and hours of operation

Hours Location

 Hours are Variable 

Joslin Diabetes center Rm 495
One Joslin Place
Boston, MA 02215



Name Role Phone Email Location
Jennifer Hollister-Lock
617 309 4391
Room 495